Synthetic Polypeptide Polymers as Simplified Analogues of Antimicrobial Peptides
نویسندگان
چکیده
منابع مشابه
Antimicrobial polymers as synthetic mimics of host-defense peptides.
Antibiotic-resistant bacteria 'superbugs' are an emerging threat to public health due to the decrease in effective antibiotics as well as the slowed pace of development of new antibiotics to replace those that become ineffective. The need for new antimicrobial agents is a well-documented issue relating to world health. Tremendous efforts have been given to developing compounds that not only sho...
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The design and generation of molecules capable of mimicking the binding and/or functional sites of proteins represents a promising strategy for the exploration and modulation of protein function through controlled interference with the underlying molecular interactions. Synthetic peptides have proven an excellent type of molecule for the mimicry of protein sites because such peptides can be gen...
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Copyright © 2012 Mathew Upton et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In developing this special issue, we sought to raise awareness of the potential of antimicrobial peptides (AMPs) for clinical use and to highligh...
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ژورنال
عنوان ژورنال: Biomacromolecules
سال: 2020
ISSN: 1525-7797,1526-4602
DOI: 10.1021/acs.biomac.0c00797